BETA-LACTAMASE DETECTION STRIP PDF Print
PRODUCTS - BETA LACTAMASE, ESBL & AMPC DETECTION

BETA-LACTAMASE DETECTION STRIP

 

b-Lactamase Test rapidly detects the presence of b-Lactamase enzyme produced
by strains of Staph aureus, Neisseria gonorrhoeae, Branhamella catarrhalis and
Haemophilus influenzae. These enzymes confer resistance to a number of penicillin
antibiotics by attacking the common b-lactam ring structure, resulting in inactivation
of these drugs. This mode of action forms the basis of the b-Lactamase test
reaction. Each strip is impregnated with benzylpenicillin and a pH indicator,
bromcresol purple. b-Lactamase positive organisms produce enzyme, which
hydrolyses benzyl penicillin forming penicilloic acid. This in turn causes a fall in pH,
which is demonstrated by a rapid change in the colour of the pH indicator from
purple to yellow. b-Lactamase Test requires only small numbers of organisms and
can be performed as soon as there is visible growth on the primary culture medium.

Beta-Lactamase Test rapidly detects the presence of Beta-Lactamase enzyme producedby strains of Staph aureus, Neisseria gonorrhoeae, Branhamella catarrhalis andHaemophilus influenzae. These enzymes confer resistance to a number of penicillinantibiotics by attacking the common Beta-lactam ring structure, resulting in inactivationof these drugs. This mode of action forms the basis of the b-Lactamase testreaction. Each strip is impregnated with benzylpenicillin and a pH indicator,bromcresol purple. Beta-Lactamase positive organisms produce enzyme, whichhydrolyses benzyl penicillin forming penicilloic acid. This in turn causes a fall in pH,which is demonstrated by a rapid change in the colour of the pH indicator frompurple to yellow. Beta-Lactamase Test requires only small numbers of organisms andcan be performed as soon as there is visible growth on the primary culture medium.

 

Pack Insert

MSDS

Next >